Cushing’s Syndrome: What is it?

This hormonal disorder arises when the body is subjected to prolonged exposure to elevated levels of the hormone cortisol.

The adrenal glands produce cortisol, which plays a crucial role in various bodily functions, encompassing the regulation of blood pressure, blood sugar levels, and the immune system.

When cortisol levels are high, it leads to a range of symptoms and health problems.

Symptoms of Cushing’s Syndrome

  • Weight gain (especially around the mid-section and upper back)
  • Facial rounding or a “moon face”
  • Purple stretch marks on the skin
  • Weakening of the bones, leading to osteoporosis
  • High blood pressure
  • Muscle weakness
  • Mood changes, including anxiety and depression
  • Increased risk of infections
  • Irregular periods or decreased libido in women
  • Erectile dysfunction in men

Risk Factor of Cushing’s Syndrome

  • Prolonged use of corticosteroid medications
  • Adrenal tumors or pituitary tumors
  • Radiation therapy to the pituitary or other parts of the body
  • Family history of Cushing’s syndrome

Diagnosis of Cushing’s Syndrome

  • Blood tests to measure cortisol levels
  • 24-hour urine collection to measure cortisol levels
  • Imaging tests, like CT scans or MRI, to identify any tumors or other abnormalities in the adrenal or pituitary glands

Treatment of Cushing’s Syndrome

Treatment for Cushing’s syndrome depends on the underlying cause. 

If the condition is caused by long-term use of corticosteroid medications, gradually tapering off the medication may be enough to reduce cortisol levels. 

If the condition is caused by a tumor, surgery to remove the tumor may be needed. 

In some cases, radiation therapy or medication to block cortisol production may also be used.

Lifestyle Changes to Deal with Cushing’s Syndrome

  • A healthy diet and regular exercise helps with weight management and bone health.
  • Reducing stress and getting enough sleep may also help reduce cortisol levels.